What is Morris Water Maze Test?
The Morris water maze is a test based on the habit of mice that are averse to being in water and are forced to swim to find a platform hidden in the water, and is widely used in cognitive memory tests to determine spatial location and orientation in rodents.
Workflow of Morris Water Maze Test
1. Preparation (animal grouping, test preparation)
2. Perform the visible platform trial
3. Perform the hidden platform trial
4. Perform the probe trial
5. Perform the reversal trial
6. Data Analysis
7. Delivery to customers
Data Analysis of Morris Water Maze Test
The Morris water maze experiment allows for the analysis and inference of learning, memory and spatial cognitive abilities by observing and recording the time it takes for animals to enter the water and search for hidden platforms, the strategies used and their swimming trajectories. The experiment has a wide range of statistical indicators that can be used to evaluate the animals. The evaluation metrics include:
Morris Water Maze Test Applications
The Morris water maze is used as a classic experiment in scientific research in a wide range of fields such as spatial cognition, learning memory, hippocampal and extrahippocampal studies, intelligence and aging, new drug development and safety evaluation, toxicology, pharmacology, animal psychology and behavioral biology.
- Research on diseases related to cognitive disorders (Alzheimer’s disease, Parkinson’s disease, vascular dementia).
- Screening of neurotoxic or therapeutic drugs.
- Effects of cortical decline or brain damage on cognitive memory.
- Effects of drugs or other experimental treatments on the eyesight of animals.